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Mouse Anti-RXRB Recombinant Antibody (CBCNR-902) (CBMAB-R3962-CN)

This product is a Mouse antibody that recognizes RXRB. The antibody CBCNR-902 can be used for immunoassay techniques such as: ELISA, WB.
See all RXRB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-902
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
RXRB (H01167.1, aa. 161-260) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
1× PBS, pH 7.2

Target

Full Name
RXRB
Introduction
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Entrez Gene ID
6257
UniProt ID
P28702
Alternative Names
Retinoid X Receptor Beta; Nuclear Receptor Subfamily 2 Group B Member 2; NR2B2; MHC Class I Promoter Binding Protein; Retinoic Acid Receptor RXR-Beta; Retinoid X Receptor, Beta; H-2RIIBP; DAUDI6; RCoR-1;
Function
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
Biological Process
Biological Process anatomical structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of bone mineralization1 PublicationIC:ComplexPortal
Biological Process positive regulation of DNA-templated transcriptionManual Assertion Based On ExperimentIDA:GO_Central
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to retinoic acidManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinoic acid receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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