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Mouse Anti-S100A14 Recombinant Antibody (CBXS-4638) (CBMAB-S1877-CQ)

This product is a mouse antibody that recognizes S100A14. The antibody CBXS-4638 can be used for immunoassay techniques such as: WB.
See all S100A14 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4638
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Recombinant full length human S100A14 (NP_065723)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
S100 Calcium Binding Protein A14
Introduction
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).
Entrez Gene ID
UniProt ID
Alternative Names
S100 Calcium Binding Protein A14; S100A15; S114; Breast Cancer Membrane Protein 84; S100 Calcium-Binding Protein A14; Protein S100-A14; BCMP84;
Function
Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
Biological Process
Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process calcium ion homeostasis1 PublicationNAS:UniProtKB
Biological Process defense response to bacteriumManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process positive regulation of granulocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of monocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process toll-like receptor 4 signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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