Mouse Anti-S100A14 Recombinant Antibody (CBXS-4638) (CBMAB-S1877-CQ)

Name: Mouse Anti-S100A14 Recombinant Antibody (CBXS-4638)
SKU: CBMAB-S1877-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4638

Application

Immunogen

Recombinant full length human S100A14 (NP_065723)

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

S100 Calcium Binding Protein A14

Introduction

This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).

Entrez Gene ID

57402

UniProt ID

Q9HCY8

Alternative Names

S100 Calcium Binding Protein A14; S100A15; S114; Breast Cancer Membrane Protein 84; S100 Calcium-Binding Protein A14; Protein S100-A14; BCMP84;

Function

Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.

Biological Process

Biological Process apoptotic processIEA:UniProtKB-KW
Biological Process calcium ion homeostasis1 PublicationNAS:UniProtKB
Biological Process defense response to bacteriumManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process positive regulation of granulocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of monocyte chemotaxisManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentIEP:UniProtKB
Biological Process toll-like receptor 4 signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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