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Mouse Anti-S1PR4 (C-terminus) Recombinant Antibody (CBFYE-1627) (CBMAB-E2289-FY)

This product is mouse antibody that recognizes S1PR4. The antibody CBFYE-1627 can be used for immunoassay techniques such as: FC, WB.
See all S1PR4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-1627
Antibody Isotype
IgG1
Application
FC, WB

Basic Information

Immunogen
Synthetic peptide corresponding to the C-terminal of EDG6
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.08% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
C-terminus

Target

Full Name
Sphingosine-1-Phosphate Receptor 4
Introduction
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.
Entrez Gene ID
8698
UniProt ID
O95977
Alternative Names
Sphingosine-1-Phosphate Receptor 4; Endothelial Differentiation, Lysophosphatidic Acid G-Protein-Coupled Receptor, 6; Endothelial Differentiation G-Protein Coupled Receptor 6; Sphingosine 1-Phosphate Receptor Edg-6; S1P Receptor Edg-6; S1P Receptor 4; EDG6
Function
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Biological Process
Biological Process activation of phospholipase C activityManual Assertion Based On ExperimentTAS:ProtInc
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cytosolic calcium ion concentrationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-50
Helical: 51-71
Cytoplasmic: 72-84
Helical: 85-105
Extracellular: 106-117
Helical: 118-138
Cytoplasmic: 139-161
Helical: 162-182
Extracellular: 183-206
Helical: 207-227
Cytoplasmic: 228-252
Helical: 253-273
Extracellular: 274-288
Helical: 289-309
Cytoplasmic: 310-384
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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