Mouse Anti-S1PR4 (C-terminus) Recombinant Antibody (CBFYE-1627) (CBMAB-E2289-FY)

Name: Mouse Anti-S1PR4 (C-terminus) Recombinant Antibody (CBFYE-1627)
SKU: CBMAB-E2289-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYE-1627

Application

FC, WB

Immunogen

Synthetic peptide corresponding to the C-terminal of EDG6

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

0.08% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

C-terminus

More Infomation

Target

Full Name

Sphingosine-1-Phosphate Receptor 4

Introduction

This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.

Entrez Gene ID

8698

UniProt ID

O95977

Alternative Names

Sphingosine-1-Phosphate Receptor 4; Endothelial Differentiation, Lysophosphatidic Acid G-Protein-Coupled Receptor, 6; Endothelial Differentiation G-Protein Coupled Receptor 6; Sphingosine 1-Phosphate Receptor Edg-6; S1P Receptor Edg-6; S1P Receptor 4; EDG6

Function

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.

Biological Process

Biological Process activation of phospholipase C activityManual Assertion Based On ExperimentTAS:ProtInc
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cytosolic calcium ion concentrationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of metabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-50
Helical: 51-71
Cytoplasmic: 72-84
Helical: 85-105
Extracellular: 106-117
Helical: 118-138
Cytoplasmic: 139-161
Helical: 162-182
Extracellular: 183-206
Helical: 207-227
Cytoplasmic: 228-252
Helical: 253-273
Extracellular: 274-288
Helical: 289-309
Cytoplasmic: 310-384

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-S1PR4 Recombinant Antibody (CBXS-0100) (CAT#: CBMAB-S3099-CQ)

Rabbit Anti-S1PR4 Recombinant Antibody (EG1028) (CAT#: CBMAB-EN1212-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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