Mouse Anti-SAG Recombinant Antibody (S128) (CBMAB-R4010-CN)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (PubMed:9565049).
Biological Process G protein-coupled receptor internalizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process rhodopsin mediated signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Membrane
Highly expressed in photoreceptor outer segments in light-exposed retina. Evenly distributed throughout rod photoreceptor cells in dark-adapted retina (By similarity).
Predominantly dectected at the proximal region of photoreceptor outer segments, near disk membranes (PubMed:3720866).
A non-progressive retinal disorder characterized by impaired night vision, often associated with nystagmus and myopia. Congenital stationary night blindness Oguchi type is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
Retinitis pigmentosa 47 (RP47):
A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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