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Mouse Anti-SARS-CoV-2 ORF7a Recombinant Antibody (CBC03) (CBMAB-CR003LY)

The product is antibody recognizes SARS-CoV-2 ORF7a . The antibody CBC003 immunoassay techniques such as: WB, ICC/IF.
See all SARS-CoV-2 ORF7a antibodies

Summary

Host Animal
Mouse
Specificity
SARS Coronavirus, SARS Coronavirus 2
Clone
CBC003
Antibody Isotype
IgG1
Application
WB, ICC/IF

Basic Information

Immunogen
The immunogen used to generate this antibody corresponds to SARS-CoV ORF7a protein (16-111 a.a.).
Specificity
SARS Coronavirus, SARS Coronavirus 2
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SARS-CoV-2 ORF7a
Alternative Names
SARS-CoV Spike, 2019-nCoV Spike, COVID-19 Spike, SARS-CoV-2 Spike
Function
Plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation.
Responsible for replication and transcription of the viral RNA genome.
Biological Process
Biological Process DNA-templated transcriptionIEA:InterPro
Biological Process induction by virus of catabolism of host mRNAIEA:UniProtKB-KW
Biological Process induction by virus of host autophagyIEA:UniProtKB-KW
Biological Process modulation by virus of host protein ubiquitinationIEA:UniProtKB-KW
Biological Process proteolysisIEA:UniProtKB-KW
Biological Process suppression by virus of host gene expressionIEA:UniProtKB-KW
Biological Process suppression by virus of host ISG15-protein conjugationIEA:UniProtKB-KW
Biological Process suppression by virus of host NF-kappaB cascadeIEA:UniProtKB-KW
Biological Process suppression by virus of host type I interferon-mediated signaling pathwayIEA:UniProtKB-KW
Biological Process viral protein processingIEA:InterPro
Biological Process viral RNA genome replicationIEA:InterPro
Cellular Location
Cytoplasm
Endoplasmic reticulum-Golgi intermediate compartment
Host cytoplasm, host perinuclear region
Host endoplasmic reticulum-Golgi intermediate compartment
Host membrane
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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