Rabbit Anti-SCAI Recombinant Antibody (CBXS-5450) (CBMAB-S2660-CQ)

Name: Rabbit Anti-SCAI Recombinant Antibody (CBXS-5450)
SKU: CBMAB-S2660-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBXS-5450

Application

WB, IP

Specificity

Human, Mouse, Rat, Monkey

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Suppressor Of Cancer Cell Invasion

Introduction

This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described.

Entrez Gene ID

Human	286205
Mouse	320271
Rat	690538
Monkey	712803

UniProt ID

Human	Q8N9R8
Mouse	Q8C8N2
Monkey	A0A1D5Q8V0

Alternative Names

Suppressor Of Cancer Cell Invasion; Suppressor Of Cancer Cell Invasion Protein; C9orf126; Chromosome 9 Open Reading Frame 126; Protein SCAI; NET40;

Function

Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.

Biological Process

Biological Process negative regulation of cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of Rho protein signal transductionISS:UniProtKB

Cellular Location

Membrane
Nucleus
Cytoplasm
Nuclear localization is required for inhibition of MRTFA.

Topology

Helical: 472-492

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rabbit Anti-SCAI Recombinant Antibody (CBXS-1506) (CAT#: CBMAB-S4359-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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