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Rabbit Anti-SCARF1 Recombinant Antibody (CBXS-1500) (CBMAB-S4353-CQ)

This product is a rabbit antibody that recognizes SCARF1. The antibody CBXS-1500 can be used for immunoassay techniques such as: WB, IP, IHC-P, ICC.
See all SCARF1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBXS-1500
Antibody Isotype
IgG
Application
WB, IP, IHC-P, ICC

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Scavenger Receptor Class F Member 1
Introduction
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
8578
UniProt ID
Q14162
Alternative Names
Scavenger Receptor Class F Member 1; Acetyl LDL Receptor; Scavenger Receptor Expressed By Endothelial Cells 1; SREC-I; SREC; Scavenger Receptor Expressed By Endothelial Cells; Scavenger Receptor Class F, Member 1; KIAA0149; SREC1;
Function
Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity).
Biological Process
Biological Process cell adhesionIEA:UniProtKB-KW
Biological Process cholesterol catabolic process1 PublicationIC:UniProtKB
Biological Process dendrite developmentIEA:Ensembl
Biological Process neuron remodelingISS:UniProtKB
Biological Process positive regulation of axon regenerationISS:UniProtKB
Biological Process positive regulation of neuron projection developmentISS:UniProtKB
Biological Process receptor-mediated endocytosisManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 20-421
Helical: 422-442
Cytoplasmic: 443-830
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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