SCARF1

The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.
Full Name
Scavenger Receptor Class F Member 1
Function
Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity).
Biological Process
Biological Process cell adhesionIEA:UniProtKB-KW
Biological Process cholesterol catabolic process1 PublicationIC:UniProtKB
Biological Process dendrite developmentIEA:Ensembl
Biological Process neuron remodelingISS:UniProtKB
Biological Process positive regulation of axon regenerationISS:UniProtKB
Biological Process positive regulation of neuron projection developmentISS:UniProtKB
Biological Process receptor-mediated endocytosisManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 20-421
Helical: 422-442
Cytoplasmic: 443-830
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Anti-SCARF1 antibodies

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Mouse Anti-SCARF1 Recombinant Antibody (CBXS-3434) (CBMAB-S6165-CQ)

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Target: SCARF1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-3434
Application*: E, F, WB
Datasheet SDS

Rabbit Anti-SCARF1 Recombinant Antibody (CBXS-1500) (CBMAB-S4353-CQ)

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Target: SCARF1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1500
Application*: WB, IP, P, IC
Datasheet SDS

Mouse Anti-SCARF1 Recombinant Antibody (CBXS-0134) (CBMAB-S3125-CQ)

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Target: SCARF1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXS-0134
Application*: E, F, WB
Datasheet SDS

Mouse Anti-SCARF1 Recombinant Antibody (CBXS-1804) (CBMAB-S0117-CQ)

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Target: SCARF1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1804
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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