Mouse Anti-SCEL Recombinant Antibody (CBXS-3165) (CBMAB-S5907-CQ)

Name: Mouse Anti-SCEL Recombinant Antibody (CBXS-3165)
SKU: CBMAB-S5907-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-3165

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa2-98 from SCEL (NP_003834) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sciellin

Introduction

The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.

Entrez Gene ID

8796

UniProt ID

O95171

Alternative Names

Sciellin;

Function

May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope.

Biological Process

Biological Process embryo development ending in birth or egg hatchingBy SimilarityISS:UniProtKB
Biological Process epidermis developmentBy SimilarityISS:UniProtKB
Biological Process keratinocyte differentiationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of canonical Wnt signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process response to mechanical stimulusManual Assertion Based On ExperimentIEP:BHF-UCL

Cellular Location

Cytoplasm
Membrane
May become cross-linked to membrane proteins by transglutaminase.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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