Mouse Anti-SCNN1D Recombinant Antibody (CBXS-4582) (CBMAB-S1822-CQ)

Name: Mouse Anti-SCNN1D Recombinant Antibody (CBXS-4582)
SKU: CBMAB-S1822-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4582

Application

ELISA

Immunogen

Partial recombinant corresponding to aa432-531 from human SCNN1D (NP_002969) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sodium channel, nonvoltage-gated 1, delta

Introduction

SCNN1D (Sodium Channel Epithelial 1 Delta Subunit) is a Protein Coding gene. Diseases associated with SCNN1D include Pseudohypoaldosteronism, Type I, Autosomal Recessive. Among its related pathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include sodium channel activity and ligand-gated sodium channel activity. An important paralog of this gene is SCNN1A.

Entrez Gene ID

6339

UniProt ID

P51172

Alternative Names

Sodium Channel Epithelial 1 Delta Subunit; Sodium Channel, Non-Voltage-Gated 1, Delta Subunit; Nonvoltage-Gated Sodium Channel 1 Subunit Delta; Sodium Channel, Nonvoltage-Gated 1, Delta; Epithelial Na(+) Channel Subunit Delta; Delta-ENaC; Delta-NaCH; ENaCd;

Function

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Biological Process

Biological Process cellular response to acidic pHManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process cellular response to aldosterone1 PublicationIC:ComplexPortal
Biological Process cellular response to amilorideManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process cellular response to vasopressin1 PublicationIC:ComplexPortal
Biological Process cellular sodium ion homeostasisManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process regulation of blood pressure1 PublicationIC:ComplexPortal
Biological Process sensory perception of salty taste1 PublicationIC:ComplexPortal
Biological Process sensory perception of sour taste1 PublicationIC:ComplexPortal
Biological Process sodium ion import across plasma membraneManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sodium ion transportManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-250
Helical: 251-271
Extracellular: 272-694
Helical: 695-715
Cytoplasmic: 716-802

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-SCNN1D Recombinant Antibody (2F3) (CAT#: CBMAB-A7935-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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