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Mouse Anti-SCXA Monoclonal Antibody (1D2) (CBMAB-0089-LY)

This product is mouse monoclonal antibody recognizes SCXA of human. The antibody 1D2 immunoassay techniques such as: IP, ELISA.
See all SCXA antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D2
Antibody Isotype
IgG2a
Application
IP, ELISA

Basic Information

Immunogen
Recombinant peptide (Full Length)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Scleraxis bHLH transcription factor
Introduction
In August, 2010 the Genome Reference Consortium determined that the region contains a duplication error. The clone on which SCXA was based (AC110280.8) was be removed from the GRCh38 reference assembly and SCXB was retained and renamed to SCX.
Entrez Gene ID
642658
UniProt ID
Q7RTU7
Alternative Names
bHLHa41; bHLHa48; SCXA; SCXB
Function
Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.
Biological Process
Biological Process BMP signaling pathwayISS:UniProtKB
Biological Process cell differentiationISS:UniProtKB
Biological Process cellular response to mechanical stimulusIEA:Ensembl
Biological Process cellular response to transforming growth factor beta stimulusIEA:Ensembl
Biological Process chondrocyte differentiationISS:UniProtKB
Biological Process collagen fibril organizationISS:UniProtKB
Biological Process deltoid tuberosity developmentISS:UniProtKB
Biological Process developmental processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA-templated transcriptionISS:UniProtKB
Biological Process embryonic skeletal system developmentIEA:Ensembl
Biological Process endochondral ossificationISS:UniProtKB
Biological Process face morphogenesisIEA:Ensembl
Biological Process heart valve formationISS:UniProtKB
Biological Process heart valve morphogenesisISS:UniProtKB
Biological Process mesoderm formationISS:UniProtKB
Biological Process negative regulation of apoptotic processISS:UniProtKB
Biological Process negative regulation of DNA-templated transcriptionIEA:Ensembl
Biological Process positive regulation of cartilage developmentISS:UniProtKB
Biological Process positive regulation of cell population proliferationISS:UniProtKB
Biological Process positive regulation of collagen biosynthetic processISS:UniProtKB
Biological Process positive regulation of DNA-templated transcriptionISS:UniProtKB
Biological Process positive regulation of gastrulationISS:UniProtKB
Biological Process positive regulation of gene expressionISS:UniProtKB
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:GO_Central
Biological Process regulation of cartilage developmentISS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sclerotome developmentIEA:Ensembl
Biological Process Sertoli cell differentiationISS:UniProtKB
Biological Process skeletal muscle cell differentiationIEA:Ensembl
Biological Process tendon cell differentiationISS:UniProtKB
Biological Process tendon developmentISS:UniProtKB
Biological Process tendon formationISS:UniProtKB
Biological Process tissue homeostasisISS:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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