Mouse Anti-SDC2 Recombinant Antibody (CBFYH-2746) (CBMAB-H3806-FY)

Name: Mouse Anti-SDC2 Recombinant Antibody (CBFYH-2746)
SKU: CBMAB-H3806-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYH-2746

Application

IHC-Fr, ELISA, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

syndecan 2

Introduction

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Entrez Gene ID

6383

UniProt ID

P34741

Alternative Names

Syndecan 2; Heparan Sulfate Proteoglycan 1, Cell Surface-Associated; Heparan Sulfate Proteoglycan Core Protein; Syndecan Proteoglycan 2; Fibroglycan; HSPG1; SYND2

Function

Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).

Biological Process

Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process dendrite morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of dendrite morphogenesisISS:UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 19-144
Helical: 145-169
Cytoplasmic: 170-201

PTM

O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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