SDC2

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq]
Full Name
syndecan 2
Function
Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
Biological Process
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process dendrite morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of dendrite morphogenesisISS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 19-144
Helical: 145-169
Cytoplasmic: 170-201
PTM
O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.
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Anti-SDC2 antibodies

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Human SDC2 ELISA Kit (V2LY-0626-LY5300)

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Target: SDC2
Sensitivity: 0.035 ng/mL
Detection Range: 0.07-10 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Sdc2 ELISA Kit (V2LY-0626-LY3113)

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Target: Sdc2
Sensitivity: 0.0076 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Rat Sdc2 ELISA Kit (V2LY-0626-LY2704)

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Target: Sdc2
Sensitivity: 0.58 ng/mL
Detection Range: 1-400 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Datasheet SDS

Mouse Recombinant SDC2 protein, His Tag (V2LY-0526-LY8944)

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Target: SDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-141
Tag: His Tag
Datasheet SDS

Human Recombinant SDC2 protein, ECD, His Tag (V2LY-0526-LY7035)

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Target: SDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-144
Tag: His Tag
Datasheet SDS

Human Recombinant SDC2 protein, ECD, hFc Tag (V2LY-0526-LY7034)

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Target: SDC2
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 19-144
Tag: hFc Tag
Datasheet SDS

Mouse Anti-SDC2 Recombinant Antibody (1B2) (CBMAB-A7944-LY)

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Target: SDC2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B2
Application*: WB, E
Datasheet SDS

Rat Anti-SDC2 Recombinant Antibody (CBXS-3418) (CBMAB-S6152-CQ)

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Target: SDC2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-3418
Application*: F
Datasheet SDS

Rat Anti-SDC2 Recombinant Antibody (CBXS-3417) (CBMAB-S6151-CQ)

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Target: SDC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3417
Application*: E, IH
Datasheet SDS

Rat Anti-SDC2 Recombinant Antibody (CBXS-1759) (CBMAB-S4581-CQ)

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Target: SDC2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1759
Application*: IH
Datasheet SDS

Mouse Anti-SDC2 Recombinant Antibody (CBXS-0162) (CBMAB-S3149-CQ)

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Target: SDC2
Host: Mouse
Specificity: Human
Clone: CBXS-0162
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-SDC2 Recombinant Antibody (CBXS-3864) (CBMAB-S1134-CQ)

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Target: SDC2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-3864
Application*: E, WB
Datasheet SDS

Rat Anti-SDC2 Recombinant Antibody (CBXS-1760) (CBMAB-S0109-CQ)

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Target: SDC2
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1760
Application*: F
Datasheet SDS

Human Anti-SDC2 Recombinant Antibody (CBXC-0857) (CBMAB-C4916-CQ)

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Target: SDC2
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0857
Application*: F
Datasheet SDS

Mouse Anti-SDC2 Recombinant Antibody (CBFYH-2746) (CBMAB-H3806-FY)

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Target: SDC2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2746
Application*: C, E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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