Mouse Anti-SDR9C7 Recombinant Antibody (CBXS-3614) (CBMAB-S0899-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXS-3614
Application
FC, WB
Immunogen
Recombinant full length human SDR9C7 (NP_683695)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Short Chain Dehydrogenase/Reductase Family 9C Member 7
Introduction
This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities.
Entrez Gene ID
UniProt ID
Alternative Names
Short Chain Dehydrogenase/Reductase Family 9C Member 7; Orphan Short-Chain Dehydrogenase/Reductase; RDH-S; SDR-O; RDHS; SDRO; Short Chain Dehydrogenase/Reductase Family 9C, Member 7;
Function
Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.
Biological Process
Biological Process retinol metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process steroid metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Granular distribution in the whole cell.
Involvement in disease
Ichthyosis, congenital, autosomal recessive 13 (ARCI13):
A form of autosomal recessive congenital ichthyosis, a disorder of keratinization with abnormal differentiation and desquamation of the epidermis, resulting in abnormal skin scaling over the whole body. The main skin phenotypes are lamellar ichthyosis (LI) and non-bullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur. Lamellar ichthyosis is a condition often associated with an embedment in a collodion-like membrane at birth; skin scales later develop, covering the entire body surface. Non-bullous congenital ichthyosiform erythroderma characterized by fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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