SDR9C7
This gene encodes a protein with similarity to the short-chain dehydrogenase/reductase (SDR) family but has not been shown to have retinoid or dehydrogenase activities.
Full Name
Short Chain Dehydrogenase/Reductase Family 9C Member 7
Function
Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity.
Biological Process
Biological Process retinol metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process steroid metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process steroid metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Granular distribution in the whole cell.
Granular distribution in the whole cell.
Involvement in disease
Ichthyosis, congenital, autosomal recessive 13 (ARCI13):
A form of autosomal recessive congenital ichthyosis, a disorder of keratinization with abnormal differentiation and desquamation of the epidermis, resulting in abnormal skin scaling over the whole body. The main skin phenotypes are lamellar ichthyosis (LI) and non-bullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur. Lamellar ichthyosis is a condition often associated with an embedment in a collodion-like membrane at birth; skin scales later develop, covering the entire body surface. Non-bullous congenital ichthyosiform erythroderma characterized by fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs.
A form of autosomal recessive congenital ichthyosis, a disorder of keratinization with abnormal differentiation and desquamation of the epidermis, resulting in abnormal skin scaling over the whole body. The main skin phenotypes are lamellar ichthyosis (LI) and non-bullous congenital ichthyosiform erythroderma (NCIE), although phenotypic overlap within the same patient or among patients from the same family can occur. Lamellar ichthyosis is a condition often associated with an embedment in a collodion-like membrane at birth; skin scales later develop, covering the entire body surface. Non-bullous congenital ichthyosiform erythroderma characterized by fine whitish scaling on an erythrodermal background; larger brownish scales are present on the buttocks, neck and legs.
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Anti-SDR9C7 antibodies
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CompareTarget: SDR9C7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4B5
Application*: F, IH, P, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 11H10
Application*: F, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B4
Application*: F, IF, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5284
Application*: F, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5261
Application*: F, IF, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4865
Application*: WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3683
Application*: F, IF, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3614
Application*: F, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5893
Application*: F, IF, WB
Target: SDR9C7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5793
Application*: F, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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