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Rat Anti-SELE Recombinant Antibody (CBYY-C2111) (CBMAB-C3549-YY)

This product is rat antibody that recognizes SELE. The antibody CBYY-C2111 can be used for immunoassay techniques such as: ELISA, FC, IHC, IP, WB
See all SELE antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYY-C2111
Antibody Isotype
IgG2b
Application
ELISA, FC, IHC, IP, WB

Basic Information

Immunogen
CD62E (LECAM, E-Selectin, ELAM1, Endothelial Leukocyte Adhesion Molecule)
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein G purified
Buffer
1 mg/mL
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Selectin E
Entrez Gene ID
20339
UniProt ID
Q3U5F6
Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Biological Process
Biological Process actin filament-based processManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process activation of phospholipase C activityManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process calcium-mediated signalingManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukocyte cell-cell adhesionManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process leukocyte migration involved in inflammatory responseManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process leukocyte tethering or rollingManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process positive regulation of leukocyte tethering or rollingISS:UniProtKB
Biological Process positive regulation of receptor internalizationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process regulation of inflammatory responseManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process response to cytokineManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to interleukin-1Manual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process response to lipopolysaccharideManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process response to tumor necrosis factorManual Assertion Based On ExperimentTAS:BHF-UCL
Cellular Location
Cell membrane
Topology
Extracellular: 22-556
Helical: 557-578
Cytoplasmic: 579-610
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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