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Rat Anti-Sell Recombinant Antibody (MAB0709) (CBMAB-L2724-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Selectin Lymphocyte (Sell). The antibody can be used for immunoassay techniques, such as IHC-P, FC.
See all Sell antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
MAB0709
Antibody Isotype
IgG2
Application
IHC-P, FC

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Selectin L
Introduction
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. It mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. It promotes initial tethering and rolling of leukocytes in endothelia (By similarity).
Entrez Gene ID
20343
UniProt ID
P18337
Alternative Names
Lnhr; CD62L; Ly-22; Lyam1; Ly-m22; Lyam-1; LECAM-1; AI528707; L-selectin; CD62 antigen-like family member L; LAM-1; LECAM1; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; lymph node homing receptor; lymphocyte antigen 22; lymphocyte surface MEL-14 antigen
Function
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641).
Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
Biological Process
Biological Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion moleculesManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukocyte cell-cell adhesionManual Assertion Based On ExperimentTAS:BHF-UCL
Biological Process leukocyte tethering or rollingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 39-332
Helical: 333-355
Cytoplasmic: 356-372
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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