Rat Anti-SEMA4F Recombinant Antibody (CBXS-1940) (CBMAB-S0144-CQ)

Name: Rat Anti-SEMA4F Recombinant Antibody (CBXS-1940)
SKU: CBMAB-S0144-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBXS-1940

Application

Immunogen

NS0-derived recombinant mouse Semaphorin 4F, Arg41-Gly667, Accession # Q9Z123

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

A saline solution, BSA

Preservative

Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

Introduction

This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

20355

UniProt ID

Q9Z123

Alternative Names

Sema W

Function

Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity).
Might also regulate differentiation of oligodendroglial precursor cells (By similarity).
Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).

Biological Process

Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinal ganglion cell axon guidanceIEA:Ensembl
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane
Postsynaptic density
Perikaryon
Cell projection, dendrite
Colocalizes with DLG4 at synapses.

Topology

Extracellular: 35-659
Helical: 660-680
Cytoplasmic: 681-770

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rat Anti-SEMA4F Recombinant Antibody (CBXS-2623) (CAT#: CBMAB-S5377-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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