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Rat Anti-SEMA4F Recombinant Antibody (CBXS-1940) (CBMAB-S0144-CQ)

This product is a rat antibody that recognizes SEMA4F. The antibody CBXS-1940 can be used for immunoassay techniques such as: FC.
See all SEMA4F antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXS-1940
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
NS0-derived recombinant mouse Semaphorin 4F, Arg41-Gly667, Accession # Q9Z123
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
A saline solution, BSA
Preservative
Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
Introduction
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
20355
UniProt ID
Q9Z123
Alternative Names
Sema W
Function
Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity).
Might also regulate differentiation of oligodendroglial precursor cells (By similarity).
Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
Biological Process
Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinal ganglion cell axon guidanceIEA:Ensembl
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Postsynaptic density
Perikaryon
Cell projection, dendrite
Colocalizes with DLG4 at synapses.
Topology
Extracellular: 35-659
Helical: 660-680
Cytoplasmic: 681-770
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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