Human SEMA4F ELISA Kit (V2LY-0626-LY1773)

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Tested Data
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Basic Information

Sensitivity
0.0031 ng/mL
Detection Range
0.005-1 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
83.5 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
Function
Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity).
Might also regulate differentiation of oligodendroglial precursor cells (By similarity).
Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
Biological Process
Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinal ganglion cell axon guidanceIEA:Ensembl
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Postsynaptic density
Perikaryon
Cell projection, dendrite
Colocalizes with DLG4 at synapses.
Topology
Extracellular: 35-659
Helical: 660-680
Cytoplasmic: 681-770
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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