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Mouse Anti-SENP8 Recombinant Antibody (CBXS-2885) (CBMAB-S5634-CQ)

This product is a mouse antibody that recognizes SENP8. The antibody CBXS-2885 can be used for immunoassay techniques such as: ELISA, WB.
See all SENP8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2885
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa113-213 from human SENP8 (NP_660205) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SUMO/sentrin specific peptidase family member 8
Introduction
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.
Entrez Gene ID
123228
UniProt ID
Q96LD8
Alternative Names
SUMO/Sentrin Peptidase Family Member, NEDD8 Specific; NEDD8-Specific Protease 1; SUMO/Sentrin Specific Peptidase Family Member 8; Sentrin/SUMO-Specific Protease SENP8; Protease, Cysteine 2; Deneddylase 1; PRSC2; NEDP1; DEN1;
Function
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Biological Process
Biological Process post-translational protein modificationTAS:Reactome
Biological Process protein deneddylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein deubiquitinationTAS:Reactome
Cellular Location
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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