Mouse Anti-SEPT1 Recombinant Antibody (1F12) (CBMAB-C4267-CN)

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Basic Information

Host Animal
Mouse
Clone
1F12
Application
ELISA, IP, WB
Immunogen
Full length recombinant corresponding to aa 1-367 from human SEPT1 (AAH12161) with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
More Infomation

Target

Full Name
Septin 1
Introduction
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]
Entrez Gene ID
UniProt ID
Alternative Names
Septin 1; Serologically Defined Breast Cancer Antigen NY-BR-24; Peanut-Like Protein 3; PNUTL3; DIFF6; LARP; Differentiation 6 (Deoxyguanosine Triphosphate Triphosphohydrolase); Septin-1; SEP1;
Function
Filament-forming cytoskeletal GTPase (By similarity).
May play a role in cytokinesis (Potential).
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Midbody
Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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