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Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-1983) (CBMAB-S4752-CQ)

This product is a mouse antibody that recognizes SERPINB2. The antibody CBXS-1983 can be used for immunoassay techniques such as: WB.
See all SERPINB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-1983
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Recombinant human Serpin B2, Glu2-Ala65, Ala99-Pro415, Accession # P05120
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Serpin Family B Member 2
Introduction
SERPINB2 (Serpin Family B Member 2) is a Protein Coding gene. Diseases associated with SERPINB2 include Lipodermatosclerosis and Gingivitis. Among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB10.
Entrez Gene ID
5055
UniProt ID
P05120
Alternative Names
HsT1201; PAI; PAI-2; PAI2; PLANH2
Function
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Biological Process
Biological Process fibrinolysisTAS:Reactome
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process wound healingIEA:Ensembl
Cellular Location
Cytoplasm
Secreted, extracellular space
PTM
The signal sequence is not cleaved.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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