SERPINB2

SERPINB2 (Serpin Family B Member 2) is a Protein Coding gene. Diseases associated with SERPINB2 include Lipodermatosclerosis and Gingivitis. Among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB10.

Full Name

Serpin Family B Member 2

Function

Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

Biological Process

Biological Process fibrinolysisTAS:Reactome
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process wound healingIEA:Ensembl

Cellular Location

Cytoplasm
Secreted, extracellular space

PTM

The signal sequence is not cleaved.

Anti-SERPINB2 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-1983) (CBMAB-S4752-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXS-1983

Application*: WB

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-0236) (CBMAB-S3213-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Specificity: Human

Clone: CBXS-0236

Application*: WB, IC, P, C, E

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-6098) (CBMAB-S2909-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Rat

Clone: CBXS-6098

Application*: WB, IC, P, C, E, IP, IF, F

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-4963) (CBMAB-S2185-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4963

Application*: F, WB

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-4755) (CBMAB-S1984-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBXS-4755

Application*: E, IP, WB

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-4165) (CBMAB-S1418-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-4165

Application*: WB, F, IH, P

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-5689) (CBMAB-S0559-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5689

Application*: F, P, WB

Mouse Anti-SERPINB2 Recombinant Antibody (CBXS-1982) (CBMAB-S0155-CQ)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-1982

Application*: F

Mouse Anti-SERPINB2 Recombinant Antibody (CBYC-P831) (CBMAB-P3650-YC)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYC-P831

Application*: WB, IC, P, E

Mouse Anti-SERPINB2 Recombinant Antibody (3A9) (CBMAB-P3649-YC)

Datasheet

SDS

Target: SERPINB2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 3A9

Application*: E, IP, WB

SERPINB2 Matched Antibody Pair (1069) (APMAB-1069LY)

Datasheet

SDS

Target: SERPINB2

Specificity: Human

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)