SERPINB2

SERPINB2 (Serpin Family B Member 2) is a Protein Coding gene. Diseases associated with SERPINB2 include Lipodermatosclerosis and Gingivitis. Among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB10.
Full Name
Serpin Family B Member 2
Function
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Biological Process
Biological Process fibrinolysisTAS:Reactome
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process wound healingIEA:Ensembl
Cellular Location
Cytoplasm
Secreted, extracellular space
PTM
The signal sequence is not cleaved.
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Anti-SERPINB2 antibodies

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Target: SERPINB2
Host: Mouse
Specificity: Human
Clone: CBXS-0236
Application*: WB, IC, P, C, E
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1983
Application*: WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat
Clone: CBXS-6098
Application*: WB, IC, P, C, E, IP, IF, F
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4963
Application*: F, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-4755
Application*: E, IP, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4165
Application*: WB, F, IH, P
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5689
Application*: F, P, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1982
Application*: F
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYC-P831
Application*: WB, IC, P, E
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3A9
Application*: E, IP, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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