SERPINB2
SERPINB2 (Serpin Family B Member 2) is a Protein Coding gene. Diseases associated with SERPINB2 include Lipodermatosclerosis and Gingivitis. Among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB10.
Full Name
Serpin Family B Member 2
Function
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Biological Process
Biological Process fibrinolysisTAS:Reactome
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process wound healingIEA:Ensembl
Biological Process negative regulation of apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process wound healingIEA:Ensembl
Cellular Location
Cytoplasm
Secreted, extracellular space
Secreted, extracellular space
PTM
The signal sequence is not cleaved.
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Anti-SERPINB2 antibodies
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CompareTarget: SERPINB2
Specificity: Human
Target: SERPINB2
Host: Mouse
Specificity: Human
Clone: CBXS-0236
Application*: WB, IC, P, C, E
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1983
Application*: WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat
Clone: CBXS-6098
Application*: WB, IC, P, C, E, IP, IF, F
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4963
Application*: F, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-4755
Application*: E, IP, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4165
Application*: WB, F, IH, P
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5689
Application*: F, P, WB
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1982
Application*: F
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBYC-P831
Application*: WB, IC, P, E
Target: SERPINB2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3A9
Application*: E, IP, WB
Target: SERPINB2
Sensitivity: 0.0053 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SERPINB2
Sensitivity: 7.66 ng/mL
Detection Range: 15-240 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SERPINB2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-415
Tag: GST Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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