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Mouse Anti-SERPINE2 Recombinant Antibody (3G12) (CBMAB-A8005-LY)


See all SERPINE2 antibodies
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Summary

Host Animal
Mouse
Specificity
Human
Clone
3G12
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SERPINE2 (NP_006207, 72 a.a. ~ 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Serpin Family E Member 2
Entrez Gene ID
5270
UniProt ID
P07093
Alternative Names
GDN; PI7; PN1; PNI
Function
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process cerebellar granular layer morphogenesisIEA:Ensembl
Biological Process detection of mechanical stimulus involved in sensory perceptionIEA:Ensembl
Biological Process innervationIEA:Ensembl
Biological Process long-term synaptic potentiationIEA:Ensembl
Biological Process mating plug formationIEA:Ensembl
Biological Process negative regulation of blood coagulationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process negative regulation of cell growthIEA:Ensembl
Biological Process negative regulation of cell population proliferationIEA:Ensembl
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of phosphatidylinositol 3-kinase signalingIEA:Ensembl
Biological Process negative regulation of plasminogen activationManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process negative regulation of platelet aggregationBy SimilarityISS:BHF-UCL
Biological Process negative regulation of protein catabolic processIEA:Ensembl
Biological Process negative regulation of protein processing1 PublicationIC:BHF-UCL
Biological Process negative regulation of proteolysisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process negative regulation of smoothened signaling pathwayIEA:Ensembl
Biological Process negative regulation of sodium ion transportIEA:Ensembl
Biological Process platelet activationIEA:Ensembl
Biological Process positive regulation of astrocyte differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process protein catabolic processIEA:Ensembl
Biological Process regulation of cell migration1 PublicationNAS:UniProtKB
Biological Process regulation of synaptic transmission, glutamatergicIEA:Ensembl
Biological Process regulation of timing of cell differentiationIEA:Ensembl
Biological Process secretion by cellIEA:Ensembl
Biological Process secretory granule organizationIEA:Ensembl
Biological Process seminal vesicle epithelium developmentIEA:Ensembl
Cellular Location
Secreted, extracellular space
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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