Mouse Anti-SERPINH1 Recombinant Antibody (CBFYC-3111) (CBMAB-C3188-FY)

Name: Mouse Anti-SERPINH1 Recombinant Antibody (CBFYC-3111)
SKU: CBMAB-C3188-FY
Rating: 5 (1 reviews)

See all SERPINH1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYC-3111

Application

Immunogen

Full-length protein

Specificity

Human

Antibody Isotype

IgG1, k

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH7.4, 50% glycerol

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Serpin Family H Member 1

Introduction

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Entrez Gene ID

871

UniProt ID

P50454

Alternative Names

Serpin Family H Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Serpin Peptidase Inhibitor, Clade H (Heat Shock Protein 47), Member 1, (Collagen Binding Protein 1); Cell Proliferation-Inducing Gene 14 Protein; Rheumatoid Arthritis-Related Antigen RA-A47; Arsenic-Transactivated Protein 3; Collagen Binding Protein 1; 47 KDa Heat Shock Protein; SERPINH2; AsTP3; HSP47; CBP1; CBP2; Serine (Or Cysteine) Proteinase Inhibitor, Clade H (Heat Shock Protein 47), Member 2, (Collagen-Binding Protein 2)

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

Biological Process

Biological Process chondrocyte development involved in endochondral bone morphogenesisIEA:Ensembl
Biological Process collagen biosynthetic processIEA:Ensembl
Biological Process collagen fibril organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein maturationIEA:Ensembl
Biological Process response to unfolded proteinManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Endoplasmic reticulum lumen

Involvement in disease

Endoplasmic reticulum lumen:
A form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SERPINH1 Recombinant Antibody (CBFYC-3111)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-SERPINH1 Recombinant Antibody (CBFYH-2756) (CAT#: CBMAB-H3819-FY)

Mouse Anti-SERPINH1 (Internal) Recombinant Antibody (134CT3.1.1) (CAT#: CBMAB-S0400-CQ)

Mouse Anti-SERPINH1 Recombinant Antibody (M16.10A1) (CAT#: CBMAB-S6403-CQ)

Mouse Anti-SERPINH1 Recombinant Antibody (CBFYH-2757) (CAT#: CBMAB-H3820-FY)

Mouse Anti-SERPINH1 Recombinant Antibody (1D2-1A6) (CAT#: CBMAB-A8007-LY)

Mouse Anti-SERPINH1 Recombinant Antibody (134CT3-1-1) (CAT#: CBMAB-R4012-CN)

Mouse Anti-SERPINH1 Recombinant Antibody (CBXS-3979) (CAT#: CBMAB-S1241-CQ)

Mouse Anti-SERPINH1 Monoclonal Antibody (CBFYH-3303) (CAT#: CBMAB-H0387-FY)

Mouse Anti-SERPINH1 Recombinant Antibody (CBFYH-2752) (CAT#: CBMAB-H3815-FY)

Mouse Anti-SERPINH1 Recombinant Antibody (CBFYH-2754) (CAT#: CBMAB-H3817-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry