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Mouse Anti-SREK1 Recombinant Antibody (1D11) (CBMAB-A8033-LY)

The product is antibody recognizes SFRS12. The antibody 1D11 immunoassay techniques such as: WB, ELISA.
See all SREK1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D11
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
SFRS12 (NP_631907, 443 a.a. ~ 508 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Splicing Regulatory Glutamic Acid And Lysine Rich Protein 1
Introduction
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM
Entrez Gene ID
140890
UniProt ID
Q8WXA9
Alternative Names
DKFZp564B176; MGC133045; SRrp508; SRrp86
Function
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).
Biological Process
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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