Mouse Anti-SFXN1 Recombinant Antibody (CBYJT-1672) (CBMAB-T0721-YJ)

Name: Mouse Anti-SFXN1 Recombinant Antibody (CBYJT-1672)
SKU: CBMAB-T0721-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBYJT-1672

Application

ELISA

Immunogen

Purified C5b-9.Immunogen type: Purified protein

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sideroflexin 1

Introduction

SFXN1 (Sideroflexin 1) is a Protein Coding gene. Diseases related to SFXN1 include Aceruloplasminemia. Gene Ontology (GO) annotations related to SFXN1 include cation transmembrane transporter activity and ion transmembrane transporter activity. An important paralog of SFXN1 is SFXN3.

Entrez Gene ID

94081

UniProt ID

Q9H9B4

Alternative Names

Sideroflexin 1; Tricarboxylate Carrier Protein; TCC; Sideroflexin-1; SLC56A1

Function

Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).
May also transport other amino acids including alanine and cysteine (PubMed:30442778).

Biological Process

Biological Process erythrocyte differentiationIEA:Ensembl
Biological Process iron ion transportIEA:Ensembl
Biological Process L-alanine transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-serine transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mitochondrial transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process one-carbon metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process serine import into mitochondrionManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Mitochondrion inner membrane

Topology

Mitochondrial matrix: 2-102
Helical: 103-120
Mitochondrial intermembrane: 121-146
Helical: 147-167
Mitochondrial matrix: 168-174
Helical: 175-195
Mitochondrial intermembrane: 196-228
Helical: 229-249
Mitochondrial matrix: 250-266
Helical: 267-287
Mitochondrial intermembrane: 288-322

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Mouse Anti-SFXN1 Recombinant Antibody (CBFYA-0149) (CAT#: CBMAB-X0215-FY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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