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Mouse Anti-SH3D19 Recombinant Antibody (5C7) (CBMAB-A8093-LY)

The product is antibody recognizes SH3D19. The antibody 5C7 immunoassay techniques such as: WB, ELISA.
See all SH3D19 antibodies
Published Data
Fig.1 Myc-tagged Eve-1 isoforms were transiently expressed in HT1080 cells and detected by Western blotting using an antiEve-1 antibody.
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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
5C7
Antibody Isotype
IgG3, κ
Application
WB, ELISA

Basic Information

Immunogen
SH3D19 (NP_001009555, 94 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SH3 domain containing 19
Entrez Gene ID
Human152503
Mouse27059
UniProt ID
HumanQ5HYK7
MouseQ91X43
Alternative Names
EBP; EVE1; Kryn; MGC105136; MGC118910; MGC118911; MGC118912; MGC118913; SH3P19
Function
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Biological Process
Biological Process cytoskeleton organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process regulation of cell morphogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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