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Mouse Anti-SH3D19 Recombinant Antibody (CBXS-3282) (CBMAB-S6022-CQ)

This product is a mouse antibody that recognizes SH3D19. The antibody CBXS-3282 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all SH3D19 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBXS-3282
Antibody Isotype
IgG3, κ
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Partial recombinant protein corresponding to aa94-204 from human SH3D19 (NP_001009555) with GST tag
Specificity
Human, Mouse
Antibody Isotype
IgG3, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SH3 domain containing 19
Introduction
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
Human152503
Mouse27059
UniProt ID
HumanQ5HYK7
MouseQ91X43
Alternative Names
SH3 Domain Containing 19; ADAM-Binding Protein Eve-1; EEN-Binding Protein; EBP; SH3 Domain-Containing Protein 19; SH3 Domain Protein D19;
Function
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Biological Process
Biological Process cytoskeleton organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process regulation of cell morphogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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