Mouse Anti-SH3D19 Recombinant Antibody (CBXS-3282) (CBMAB-S6022-CQ)

Name: Mouse Anti-SH3D19 Recombinant Antibody (CBXS-3282)
SKU: CBMAB-S6022-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-3282

Application

ELISA, IF, IHC, WB

Immunogen

Partial recombinant protein corresponding to aa94-204 from human SH3D19 (NP_001009555) with GST tag

Specificity

Human, Mouse

Antibody Isotype

IgG3, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SH3 domain containing 19

Introduction

This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

Human	152503
Mouse	27059

UniProt ID

Human	Q5HYK7
Mouse	Q91X43

Alternative Names

SH3 Domain Containing 19; ADAM-Binding Protein Eve-1; EEN-Binding Protein; EBP; SH3 Domain-Containing Protein 19; SH3 Domain Protein D19;

Function

May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Biological Process

Biological Process cytoskeleton organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process regulation of cell morphogenesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cytoplasm
Nucleus
Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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