Rabbit Anti-SH3GL3 (Internal) Recombinant Antibody (CBXS-0346) (CBMAB-S3317-CQ)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Rabbit
Clone
CBXS-0346
Application
WB
Specificity
Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
Internal
More Infomation

Target

Full Name
SH3-domain GRB2-like 3
Entrez Gene ID
UniProt ID
Alternative Names
EEN-B2; SH3P13; Sh3d2c; Sh3d2c2
Function
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Biological Process
Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of clathrin-dependent endocytosisIEA:Ensembl
Biological Process positive regulation of neuron differentiationIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process synaptic vesicle uncoatingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Early endosome membrane
Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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