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Mouse Anti-SHISA5 Recombinant Antibody (3G5) (CBMAB-A8115-LY)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
3G5
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SHISA5 (AAH01463, 1 a.a. ~ 137 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
shisa homolog 5 (Xenopus laevis)
Entrez Gene ID
UniProt ID
Alternative Names
SCOTIN; hShisa5
Function
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Biological Process
Biological Process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIEA:Ensembl
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signalingManual Assertion Based On ExperimentHMP:UniProtKB
Cellular Location
Endoplasmic reticulum membrane
Nucleus membrane
Topology
Extracellular: 29-105
Helical: 106-126
Cytoplasmic: 127-240
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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