Mouse Anti-SHISA5 Recombinant Antibody (CBXS-4917) (CBMAB-S2139-CQ)

Name: Mouse Anti-SHISA5 Recombinant Antibody (CBXS-4917)
SKU: CBMAB-S2139-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4917

Application

ELISA, WB

Immunogen

SHISA5 (AAH01463, 1 a.a.-137 a.a) Full length recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

shisa homolog 5 (Xenopus laevis)

Introduction

This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. Related pseudogenes of this gene are found on chromosome X.

Entrez Gene ID

51246

UniProt ID

Q8N114

Alternative Names

Shisa Family Member 5; Putative NF-Kappa-B-Activating Protein 120; SCOTIN; Shisa Homolog 5 (Xenopus Laevis); Protein Shisa-5; Shisa Homolog 5;

Function

Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.

Biological Process

Biological Process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorIEA:Ensembl
Biological Process positive regulation of I-kappaB kinase/NF-kappaB signalingManual Assertion Based On ExperimentHMP:UniProtKB

Cellular Location

Endoplasmic reticulum membrane
Nucleus membrane

Topology

Extracellular: 29-105
Helical: 106-126
Cytoplasmic: 127-240

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-SHISA5 Recombinant Antibody (3G5) (CAT#: CBMAB-A8115-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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