Mouse Anti-SI Recombinant Antibody (CBXS-5675) (CBMAB-S0545-CQ)

Name: Mouse Anti-SI Recombinant Antibody (CBXS-5675)
SKU: CBMAB-S0545-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5675

Application

Immunogen

Normal human jejunal epithelial brush border-enriched membranes from a non-secretor and blood group O

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

sucrase-isomaltase (alpha-glucosidase)

Introduction

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.

Entrez Gene ID

6476

UniProt ID

P14410

Alternative Names

Sucrase-Isomaltase; Oligosaccharide Alpha-1,6-Glucosidase; Alpha-Glucosidase; Sucrase-Isomaltase (Alpha-Glucosidase); Sucrase-Isomaltase, Intestinal; EC 3.2.1.20;

Function

Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.

Biological Process

Biological Process polysaccharide digestionTAS:Reactome
Biological Process sucrose catabolic processManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Apical cell membrane

Topology

Cytoplasmic: 2-12
Helical: 13-32
Lumenal: 33-1827

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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