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Mouse Anti-SI Recombinant Antibody (CBXS-5675) (CBMAB-S0545-CQ)

This product is a mouse antibody that recognizes SI. The antibody CBXS-5675 can be used for immunoassay techniques such as: IP.
See all SI antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5675
Application
IP

Basic Information

Immunogen
Normal human jejunal epithelial brush border-enriched membranes from a non-secretor and blood group O
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
sucrase-isomaltase (alpha-glucosidase)
Introduction
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.
Entrez Gene ID
6476
UniProt ID
P14410
Alternative Names
Sucrase-Isomaltase; Oligosaccharide Alpha-1,6-Glucosidase; Alpha-Glucosidase; Sucrase-Isomaltase (Alpha-Glucosidase); Sucrase-Isomaltase, Intestinal; EC 3.2.1.20;
Function
Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.
Biological Process
Biological Process polysaccharide digestionTAS:Reactome
Biological Process sucrose catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Apical cell membrane
Topology
Cytoplasmic: 2-12
Helical: 13-32
Lumenal: 33-1827
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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