SI

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.
Full Name
sucrase-isomaltase (alpha-glucosidase)
Function
Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides.
Biological Process
Biological Process polysaccharide digestionTAS:Reactome
Biological Process sucrose catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Apical cell membrane
Topology
Cytoplasmic: 2-12
Helical: 13-32
Lumenal: 33-1827
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Anti-SI antibodies

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Mouse Anti-SI Antibody (HBB2/614/88) (CBMAB-1564CQ)

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Target: SI
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HBB2/614/88
Application*: E, P, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-SI Antibody (HBB2/219/20) (CBMAB-1563CQ)

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Target: SI
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: HBB2/219/20
Application*: E, IF, IH, IP
Datasheet SDS

Mouse Anti-SI Recombinant Antibody (1A8) (CBMAB-A8118-LY)

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Target: SI
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1A8
Application*: WB, E
Datasheet SDS

Mouse Anti-SI Recombinant Antibody (CBXS-3838) (CBMAB-S1108-CQ)

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Target: SI
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-3838
Application*: E, WB
Datasheet SDS

Mouse Anti-SI Recombinant Antibody (CBXS-5675) (CBMAB-S0545-CQ)

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Target: SI
Host: Mouse
Specificity: Human
Clone: CBXS-5675
Application*: IP
Datasheet SDS

Mouse Anti-SI Recombinant Antibody (CBXO-0055) (CBMAB-O0401-CQ)

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Target: SI
Host: Mouse
Specificity: Human
Clone: CBXO-0055
Application*: WB, IC, P, C, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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