Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157)

Name: Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689)
SKU: V2LY-0625-LY1157
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in ELISA

Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in WB

Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in FC

Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in IF

Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBT2689

Application

ICC, FC

Immunogen

Purified recombinant fragment of human CD169 (AA: extra 20-197) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
ICC	1:200-1:1,000
FC	1:200-1:400
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Sialic Acid Binding Ig Like Lectin 1

Entrez Gene ID

6614

Function

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).
Binds to SPN/CD43 on T-cells (By similarity).
May play a role in hemopoiesis.

Biological Process

Biological Process cell-cell adhesion1 PublicationNAS:UniProtKB
Biological Process cell-matrix adhesion1 PublicationNAS:UniProtKB
Biological Process clathrin-dependent endocytosis of virus by host cellManual Assertion Based On ExperimentIBA:GO_Central
Biological Process inflammatory response1 PublicationNAS:UniProtKB

Cellular Location

Isoform 1
Cell membrane
Isoform 2
Secreted

Topology

Extracellular: 20-1641
Helical: 1642-1662
Cytoplasmic: 1663-1709

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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