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Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157)


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Tested Data
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in ELISA
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in ELISA
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in WB
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in WB
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in WB
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in WB
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in FC
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in FC
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in IF
Mouse Anti-SIGLEC1 Recombinant Antibody (CBT2689) (V2LY-0625-LY1157) in IF

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT2689
Antibody Isotype
IgG2a
Application
ICC, FC

Basic Information

Immunogen
Purified recombinant fragment of human CD169 (AA: extra 20-197) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Entrez Gene ID
6614
Function
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).
Binds to SPN/CD43 on T-cells (By similarity).
May play a role in hemopoiesis.
Biological Process
Biological Process cell-cell adhesion1 PublicationNAS:UniProtKB
Biological Process cell-matrix adhesion1 PublicationNAS:UniProtKB
Biological Process clathrin-dependent endocytosis of virus by host cellManual Assertion Based On ExperimentIBA:GO_Central
Biological Process inflammatory response1 PublicationNAS:UniProtKB
Cellular Location
Isoform 1
Cell membrane
Isoform 2
Secreted
Topology
Extracellular: 20-1641
Helical: 1642-1662
Cytoplasmic: 1663-1709
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For research use only. Not intended for any clinical use.

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