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Mouse Anti-SLA Recombinant Antibody (CBXS-4324) (CBMAB-S1569-CQ)

This product is a mouse antibody that recognizes SLA. The antibody CBXS-4324 can be used for immunoassay techniques such as: ELISA, WB.
See all SLA antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4324
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Src-like-adaptor
Entrez Gene ID
UniProt ID
Alternative Names
Src Like Adaptor; Src-Like-Adapter Protein 1; Src-Like-Adapter; SLAP-1; HSLAP; SLAP; Src-Like-Adaptor; SLAP1; SLA1;
Function
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Biological Process
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process innate immune responseManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of signal transductionIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Endosome
Colocalizes with endosomes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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