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Mouse Anti-SLC15A1 Recombinant Antibody (CBXS-4138) (CBMAB-S1392-CQ)

This product is a mouse antibody that recognizes SLC15A1. The antibody CBXS-4138 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC15A1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4138
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 15 (oligopeptide transporter), member 1
Introduction
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.
Entrez Gene ID
6564
UniProt ID
P46059
Alternative Names
Solute Carrier Family 15 Member 1; Solute Carrier Family 15 (Oligopeptide Transporter), Member 1; Oligopeptide Transporter, Small Intestine Isoform; Peptide Transporter 1; PEPT1; BA551M18.1.1 (Solute Carrier Family 15 (Oligopeptide Transporter) Member 1); Solute Carrier Family 15 Oligopeptide Transporter Member 1; Macrophage Oligopeptide Transporter PEPT1;
Function
Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7896779, PubMed:18367661, PubMed:19685173).
Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity).
Biological Process
Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ion transportTAS:Reactome
Biological Process protein transportIEA:UniProtKB-KW
Biological Process tripeptide import across plasma membraneISS:ARUK-UCL
Cellular Location
Membrane
Topology
Helical: 1-21
Extracellular: 22-53
Helical: 54-74
Cytoplasmic: 75-82
Helical: 83-103
Extracellular: 104-118
Helical: 119-139
Cytoplasmic: 140-161
Helical: 162-182
Extracellular: 183-198
Helical: 199-219
Cytoplasmic: 220-276
Helical: 277-297
Extracellular: 298-327
Helical: 328-348
Cytoplasmic: 349-361
Helical: 362-382
Extracellular: 383-584
Helical: 585-605
Cytoplasmic: 606-619
Helical: 620-640
Extracellular: 641-645
Helical: 646-666
Cytoplasmic: 667-708
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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