Mouse Anti-SLC15A1 Recombinant Antibody (CBXS-4138) (CBMAB-S1392-CQ)

Name: Mouse Anti-SLC15A1 Recombinant Antibody (CBXS-4138)
SKU: CBMAB-S1392-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-4138

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 15 (oligopeptide transporter), member 1

Introduction

This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.

Entrez Gene ID

6564

UniProt ID

P46059

Alternative Names

Solute Carrier Family 15 Member 1; Solute Carrier Family 15 (Oligopeptide Transporter), Member 1; Oligopeptide Transporter, Small Intestine Isoform; Peptide Transporter 1; PEPT1; BA551M18.1.1 (Solute Carrier Family 15 (Oligopeptide Transporter) Member 1); Solute Carrier Family 15 Oligopeptide Transporter Member 1; Macrophage Oligopeptide Transporter PEPT1;

Function

Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7896779, PubMed:18367661, PubMed:19685173).
Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity).

Biological Process

Biological Process dipeptide import across plasma membraneManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ion transportTAS:Reactome
Biological Process protein transportIEA:UniProtKB-KW
Biological Process tripeptide import across plasma membraneISS:ARUK-UCL

Cellular Location

Membrane

Topology

Helical: 1-21
Extracellular: 22-53
Helical: 54-74
Cytoplasmic: 75-82
Helical: 83-103
Extracellular: 104-118
Helical: 119-139
Cytoplasmic: 140-161
Helical: 162-182
Extracellular: 183-198
Helical: 199-219
Cytoplasmic: 220-276
Helical: 277-297
Extracellular: 298-327
Helical: 328-348
Cytoplasmic: 349-361
Helical: 362-382
Extracellular: 383-584
Helical: 585-605
Cytoplasmic: 606-619
Helical: 620-640
Extracellular: 641-645
Helical: 646-666
Cytoplasmic: 667-708

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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