Sign in or Register   Sign in or Register
  |  

Mouse Anti-SLC22A13 Recombinant Antibody (CBXS-2767) (CBMAB-S5518-CQ)

This product is a mouse antibody that recognizes SLC22A13. The antibody CBXS-2767 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC22A13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2767
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa38-139 from SLC22A13 (NP_004247) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 22 (organic anion transporter), member 13
Introduction
This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.
Entrez Gene ID
9390
UniProt ID
Q9Y226
Alternative Names
Solute Carrier Family 22 Member 13; Solute Carrier Family 22 (Organic Anion/Urate Transporter), Member 13; Solute Carrier Family 22 (Organic Anion Transporter), Member 13; Organic Cationic Transporter-Like 3; ORCTL-3; ORCTL3;
Function
Anion antiporter that mediates the transport of urate, orotate and nicotinate in exchange for organic or inorganic anions (PubMed:18411268, PubMed:35144162, PubMed:31780526, PubMed:35462902).
Translocates urate and orotate across the apical membrane of proximal tubule epithelial cells and involved in urate renal reabsorption (PubMed:18411268, PubMed:35144162, PubMed:31780526).
Possibly involved in orotate renal reabsorption and nicotinate intestinal reabsorption (PubMed:18411268, PubMed:35144162).
Mediates urate uptake by an exchange with organic anions such as (S)-lactate, succinate, glutathione and nicotinate (PubMed:18411268).
Urate and orotate transports are Cl--dependent (PubMed:35144162, PubMed:35462902).
Shows similar transport characteristics as the urate/orotate renal antiporter SLC22A12/URAT1 and may act as a compensator of SLC22A12/URAT1 in certain conditions (Probable).
Biological Process
Biological Process NAD biosynthesis via nicotinamide riboside salvage pathwayTAS:Reactome
Biological Process negative regulation of fatty acid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process nicotinate transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of T cell mediated cytotoxicity directed against tumor cell targetManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process urate transportManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Apical cell membrane
PTM
Glycosylated.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-SLC22A13 Recombinant Antibody (CBXS-2767)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare