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Mouse Anti-SLC25A14 Recombinant Antibody (CBXS-2713) (CBMAB-S5464-CQ)

This product is a mouse antibody that recognizes SLC25A14. The antibody CBXS-2713 can be used for immunoassay techniques such as: ELISA.
See all SLC25A14 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2713
Application
ELISA

Basic Information

Immunogen
SLC25A14 (NP_003942.1, 1aa-325aa) Full length recombinant protein with GST tag
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 25 (mitochondrial carrier, brain), member 14
Introduction
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4.
Entrez Gene ID
9016
UniProt ID
O95258
Alternative Names
Solute Carrier Family 25 Member 14; Mitochondrial Uncoupling Protein 5; BMCP1; UCP5; Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14; Brain Mitochondrial Carrier Protein 1; BMCP-1; UCP 5;
Function
Participates in the mitochondrial proton leak measured in brain mitochondria.
Biological Process
Biological Process aerobic respirationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process malate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mitochondrial transportIEA:InterPro
Biological Process oxaloacetate transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phosphate ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process succinate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sulfate transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process thiosulfate transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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