Mouse Anti-SLC25A14 Recombinant Antibody (CBXS-2713) (CBMAB-S5464-CQ)

Name: Mouse Anti-SLC25A14 Recombinant Antibody (CBXS-2713)
SKU: CBMAB-S5464-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2713

Application

ELISA

Immunogen

SLC25A14 (NP_003942.1, 1aa-325aa) Full length recombinant protein with GST tag

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 25 (mitochondrial carrier, brain), member 14

Introduction

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4.

Entrez Gene ID

9016

UniProt ID

O95258

Alternative Names

Solute Carrier Family 25 Member 14; Mitochondrial Uncoupling Protein 5; BMCP1; UCP5; Solute Carrier Family 25 (Mitochondrial Carrier, Brain), Member 14; Brain Mitochondrial Carrier Protein 1; BMCP-1; UCP 5;

Function

Participates in the mitochondrial proton leak measured in brain mitochondria.

Biological Process

Biological Process aerobic respirationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process malate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mitochondrial transportIEA:InterPro
Biological Process oxaloacetate transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phosphate ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process succinate transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sulfate transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process thiosulfate transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Mitochondrion inner membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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