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Mouse Anti-SLC25A25 Recombinant Antibody (CBXS-5025) (CBMAB-S2247-CQ)

This product is a mouse antibody that recognizes SLC25A25. The antibody CBXS-5025 can be used for immunoassay techniques such as: WB, IP, ELISA.
See all SLC25A25 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5025
Antibody Isotype
IgG2a, κ
Application
WB, IP, ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa2-111 from human SLC25A25 (NP_443133) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
Introduction
The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.
Entrez Gene ID
114789
UniProt ID
Q6KCM7
Alternative Names
Solute Carrier Family 25 Member 25; Solute Carrier Family 25 (Mitochondrial Carrier; Phosphate Carrier), Member 25; Mitochondrial Ca(2+)-Dependent Solute Carrier Protein 3; Mitochondrial ATP-Mg/Pi Carrier Protein 3; Calcium-Binding Mitochondrial Carrier Protein SCaMC-2; Small Calcium-Binding Mitochondrial Carrier Protein 2; Short Calcium-Binding Mitochondrial Carrier 2; Small Calcium-Binding Mitochondrial Carrier 2;
Function
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
Biological Process
Biological Process adipose tissue developmentIEA:Ensembl
Biological Process ATP metabolic processIEA:Ensembl
Biological Process calcium ion transmembrane transportIEA:Ensembl
Biological Process camera-type eye developmentIEA:Ensembl
Biological Process cellular respirationIEA:Ensembl
Biological Process multicellular organism growthIEA:Ensembl
Biological Process response to activityIEA:Ensembl
Biological Process response to dietary excessIEA:Ensembl
Biological Process response to foodIEA:Ensembl
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial intermembrane: 1-189
Helical: 190-207
Mitochondrial matrix: 208-244
Helical: 245-264
Mitochondrial intermembrane: 265-287
Helical: 288-301
Mitochondrial matrix: 302-337
Helical: 338-357
Mitochondrial intermembrane: 358-380
Helical: 381-398
Mitochondrial matrix: 399-437
Helical: 438-457
Mitochondrial intermembrane: 458-469
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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