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Mouse Anti-SLC26A7 Recombinant Antibody (14H5) (CBMAB-S0217-CQ)

This product is a mouse antibody that recognizes SLC26A7. The antibody 14H5 can be used for immunoassay techniques such as: IF, WB.
See all SLC26A7 antibodies
Published Data

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
14H5
Antibody Isotype
IgG2a
Application
IF, WB

Basic Information

Immunogen
A fusion protein containing the C-terminal region of mouse SLC26A7. [Swiss-Prot# Q24JS8]
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Tris glycine, 0.15 M NaCl
Preservative
0.05% sodium azide
Concentration
1.7 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 26 Member 7
Introduction
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described.
Entrez Gene ID
Human115111
Mouse208890
UniProt ID
HumanQ8TE54
MouseQ8R2Z3
Alternative Names
Solute Carrier Family 26 Member 7; Solute Carrier Family 26 (Anion Exchanger), Member 7; Anion Exchange Transporter; SUT2; Solute Carrier Family 26, Member 7; Sulfate Anion Transporter;
Function
Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger. Plays a major role in gastric acid secretion.
Biological Process
Biological Process anion transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process bicarbonate transportBy SimilarityISS:UniProtKB
Biological Process chloride transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process gastric acid secretionIEA:Ensembl
Biological Process ion transportTAS:Reactome
Biological Process oxalate transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process sulfate transportManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Recycling endosome membrane
Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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