Mouse Anti-SLC27A3 Recombinant Antibody (CBXS-3101) (CBMAB-S5846-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXS-3101
Application
ELISA
Immunogen
Partial recombinant corresponding to aa635-731 from human SLC27A3 (NP_077306) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
solute carrier family 27 (fatty acid transporter), member 3
Introduction
This gene belongs to a family of integral membrane proteins and encodes a protein that is involved in lipid metabolism. The increased expression of this gene in human neural stem cells derived from induced pluripotent stem cells suggests that it plays an important role in early brain development. Naturally occurring mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
UniProt ID
Alternative Names
Solute Carrier Family 27 Member 3; Solute Carrier Family 27 (Fatty Acid Transporter), Member 3; Very Long-Chain Acyl-CoA Synthetase Homolog 3; ACSVL3; VLCS-3; FATP3; Long-Chain Fatty Acid Transport Protein 3;
Function
Mainly functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:23936004).
Can mediate the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across membranes (By similarity).
Biological Process
Biological Process fatty acid transportManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process long-chain fatty acid metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Mitochondrion membrane
Topology
Helical: 3-23
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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