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Mouse Anti-SLC30A3 Recombinant Antibody (CBXS-4652) (CBMAB-S1891-CQ)

This product is a mouse antibody that recognizes SLC30A3. The antibody CBXS-4652 can be used for immunoassay techniques such as: FC, IF, WB.
See all SLC30A3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4652
Antibody Isotype
IgG3
Application
FC, IF, WB

Basic Information

Immunogen
Recombinant full length human SLC30A3 (NP_003450)
Specificity
Human
Antibody Isotype
IgG3
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 30 Member 3
Entrez Gene ID
7781
UniProt ID
Q99726
Alternative Names
Solute Carrier Family 30 Member 3; Solute Carrier Family 30 (Zinc Transporter), Member 3; ZnT-3; ZNT3; Zinc Transporter ZnT-3; Zinc Transporter 3;
Function
Zinc ion transporter mediating the import of zinc from cytoplasm into synaptic vesicles and participating to cellular zinc ion homeostasis in the brain.
Biological Process
Biological Process positive regulation of transportIEA:Ensembl
Biological Process regulation of sequestering of zinc ionManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process response to zinc ionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion import into synaptic vesicleIEA:Ensembl
Biological Process zinc ion transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Synapse, synaptosome
Late endosome membrane
Lysosome membrane
Involvement in disease
Homodimerization through dityrosine bonds is stimulated by oxidative stress.
Topology
Cytoplasmic: 1-75
Helical: 76-96
Lumenal: 97-105
Helical: 106-126
Cytoplasmic: 127-145
Helical: 146-166
Lumenal: 167-177
Helical: 178-198
Cytoplasmic: 199-235
Helical: 236-256
Lumenal: 257-264
Helical: 265-285
Cytoplasmic: 286-388
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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