SLC30A3
SLC30A3(solute carrier family 30 member 3) is a protein coding gene
Full Name
Solute Carrier Family 30 Member 3
Function
Zinc ion transporter mediating the import of zinc from cytoplasm into synaptic vesicles and participating to cellular zinc ion homeostasis in the brain.
Biological Process
Biological Process positive regulation of transportIEA:Ensembl
Biological Process regulation of sequestering of zinc ionManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process response to zinc ionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion import into synaptic vesicleIEA:Ensembl
Biological Process zinc ion transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of sequestering of zinc ionManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process response to zinc ionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion import into synaptic vesicleIEA:Ensembl
Biological Process zinc ion transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Synapse, synaptosome
Late endosome membrane
Lysosome membrane
Synapse, synaptosome
Late endosome membrane
Lysosome membrane
Involvement in disease
Homodimerization through dityrosine bonds is stimulated by oxidative stress.
Topology
Cytoplasmic: 1-75
Helical: 76-96
Lumenal: 97-105
Helical: 106-126
Cytoplasmic: 127-145
Helical: 146-166
Lumenal: 167-177
Helical: 178-198
Cytoplasmic: 199-235
Helical: 236-256
Lumenal: 257-264
Helical: 265-285
Cytoplasmic: 286-388
Helical: 76-96
Lumenal: 97-105
Helical: 106-126
Cytoplasmic: 127-145
Helical: 146-166
Lumenal: 167-177
Helical: 178-198
Cytoplasmic: 199-235
Helical: 236-256
Lumenal: 257-264
Helical: 265-285
Cytoplasmic: 286-388
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Anti-SLC30A3 antibodies
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Target: SLC30A3
Sensitivity: 0.011 ng/mL
Detection Range: 0.02-6 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: SLC30A3
Sensitivity: 0.0092 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Slc30a3
Sensitivity: 0.013 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Target: SLC30A3
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBXS-4652
Application*: F, IF, WB
Target: SLC30A3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Mouse
Clone: CBWJZ-265
Application*: IC, IP, WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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