Mouse Anti-SLC30A6 Recombinant Antibody (2G6-G3) (CBMAB-S2839-CQ)

Name: Mouse Anti-SLC30A6 Recombinant Antibody (2G6-G3)
SKU: CBMAB-S2839-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2G6-G3

Application

ELISA

Immunogen

SLC30A6 (AAH32525, 1 a.a.-216 a.a) Full length recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 30 (zinc transporter), member 6

Introduction

This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques.

Entrez Gene ID

55676

UniProt ID

Q6NXT4

Alternative Names

Solute Carrier Family 30 Member 6; Solute Carrier Family 30 (Zinc Transporter), Member 6; ZNT6; Zinc Transporter 6; MSTP103; MST103; ZnT-6;

Function

Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.

Biological Process

Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process insulin processingTAS:Reactome
Biological Process zinc ion import into organelle1 PublicationIC:UniProtKB
Biological Process zinc ion transmembrane transportTAS:Reactome
Biological Process zinc ion transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Golgi apparatus, trans-Golgi network membrane
Found in vesicles.

Topology

Cytoplasmic: 1-33
Helical: 34-54
Extracellular: 55-64
Helical: 65-85
Cytoplasmic: 86-98
Helical: 99-119
Extracellular: 120-134
Helical: 135-155
Cytoplasmic: 156-200
Helical: 201-221
Extracellular: 222-223
Helical: 224-244
Cytoplasmic: 245-461

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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