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Mouse Anti-SLC30A6 Recombinant Antibody (2G6-G3) (CBMAB-S2839-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2G6-G3
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
SLC30A6 (AAH32525, 1 a.a.-216 a.a) Full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 30 (zinc transporter), member 6
Introduction
This gene encodes a member of a family of proteins that function as zinc transporters. This protein can regulate subcellular levels of zinc in the Golgi and vesicles. Expression of this gene is altered in the Alzheimer's disease brain plaques.
Entrez Gene ID
55676
UniProt ID
Q6NXT4
Alternative Names
Solute Carrier Family 30 Member 6; Solute Carrier Family 30 (Zinc Transporter), Member 6; ZNT6; Zinc Transporter 6; MSTP103; MST103; ZnT-6;
Function
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
Biological Process
Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process insulin processingTAS:Reactome
Biological Process zinc ion import into organelle1 PublicationIC:UniProtKB
Biological Process zinc ion transmembrane transportTAS:Reactome
Biological Process zinc ion transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Golgi apparatus, trans-Golgi network membrane
Found in vesicles.
Topology
Cytoplasmic: 1-33
Helical: 34-54
Extracellular: 55-64
Helical: 65-85
Cytoplasmic: 86-98
Helical: 99-119
Extracellular: 120-134
Helical: 135-155
Cytoplasmic: 156-200
Helical: 201-221
Extracellular: 222-223
Helical: 224-244
Cytoplasmic: 245-461
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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