SLC30A6

Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM

Full Name

solute carrier family 30 (zinc transporter), member 6

Function

Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.

Biological Process

Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process insulin processingTAS:Reactome
Biological Process zinc ion import into organelle1 PublicationIC:UniProtKB
Biological Process zinc ion transmembrane transportTAS:Reactome
Biological Process zinc ion transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Golgi apparatus, trans-Golgi network membrane
Found in vesicles.

Topology

Cytoplasmic: 1-33
Helical: 34-54
Extracellular: 55-64
Helical: 65-85
Cytoplasmic: 86-98
Helical: 99-119
Extracellular: 120-134
Helical: 135-155
Cytoplasmic: 156-200
Helical: 201-221
Extracellular: 222-223
Helical: 224-244
Cytoplasmic: 245-461

Anti-SLC30A6 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-SLC30A6 Recombinant Antibody (2G6-G3) (CBMAB-S2839-CQ)

Datasheet

SDS

Target: SLC30A6

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2G6-G3

Application*: E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)