Mouse Anti-SLC35D2 Recombinant Antibody (CBXS-2813) (CBMAB-S5564-CQ)

Name: Mouse Anti-SLC35D2 Recombinant Antibody (CBXS-2813)
SKU: CBMAB-S5564-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBXS-2813

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa74-132 from human SLC35D2 (NP_008932) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, λ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 35, member D2

Introduction

Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).

Entrez Gene ID

11046

UniProt ID

Q76EJ3

Alternative Names

Solute Carrier Family 35 Member D2; Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2; UDP-Galactose Transporter-Related Protein 8; Homolog Of Fringe Connection Protein 1; SQV7-Like Protein; UGTrel8; HFRC1;

Function

Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.

Biological Process

Biological Process carbohydrate transportIEA:UniProtKB-KW
Biological Process glycosaminoglycan biosynthetic processTAS:Reactome
Biological Process keratan sulfate biosynthetic processTAS:Reactome

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-27
Helical: 28-48
Extracellular: 49-53
Helical: 54-74
Cytoplasmic: 75-146
Helical: 147-188
Cytoplasmic: 189-201
Helical: 202-222
Extracellular: 223-237
Helical: 238-258
Cytoplasmic: 259-265
Helical: 266-288
Extracellular: 289-292
Helical: 293-315
Cytoplasmic: 316-337

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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