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Mouse Anti-SLC35D2 Recombinant Antibody (CBXS-2813) (CBMAB-S5564-CQ)

This product is a mouse antibody that recognizes SLC35D2. The antibody CBXS-2813 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC35D2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2813
Antibody Isotype
IgG2a, λ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa74-132 from human SLC35D2 (NP_008932) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, λ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 35, member D2
Introduction
Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).
Entrez Gene ID
11046
UniProt ID
Q76EJ3
Alternative Names
Solute Carrier Family 35 Member D2; Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member D2; UDP-Galactose Transporter-Related Protein 8; Homolog Of Fringe Connection Protein 1; SQV7-Like Protein; UGTrel8; HFRC1;
Function
Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
Biological Process
Biological Process carbohydrate transportIEA:UniProtKB-KW
Biological Process glycosaminoglycan biosynthetic processTAS:Reactome
Biological Process keratan sulfate biosynthetic processTAS:Reactome
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-27
Helical: 28-48
Extracellular: 49-53
Helical: 54-74
Cytoplasmic: 75-146
Helical: 147-188
Cytoplasmic: 189-201
Helical: 202-222
Extracellular: 223-237
Helical: 238-258
Cytoplasmic: 259-265
Helical: 266-288
Extracellular: 289-292
Helical: 293-315
Cytoplasmic: 316-337
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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