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Mouse Anti-SLC38A4 Recombinant Antibody (CBXS-2023) (CBMAB-S4790-CQ)

This product is a mouse antibody that recognizes SLC38A4. The antibody CBXS-2023 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SLC38A4 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat
Clone
CBXS-2023
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 38 Member 4
Introduction
SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001 [PubMed 11342143]).
Entrez Gene ID
Mouse69354
Rat170573
UniProt ID
MouseQ8R1S9
RatQ9EQ25
Alternative Names
1110012E16Rik; 1700012A18Rik; Ata3; mATA3; mNAT3
Function
Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:11342143, PubMed:19015196, PubMed:33928121).
The transport is electrogenic, pH dependent and partially tolerates substitution of Na+ by Li+ (PubMed:11414754).
Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine (PubMed:11414754, PubMed:33928121).
Biological Process
Biological Process amino acid transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process amino acid transportTAS:Reactome
Biological Process sodium ion transportIEA:UniProtKB-KW
Cellular Location
Cell membrane
Cell projection, microvillus membrane
Microvillus membrane localization in placenta.
PTM
The disulfide bond plays an important role in substrate transport, but has no effect on trafficking to the cell surface.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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