Mouse Anti-SLC38A4 Recombinant Antibody (CBXS-2219) (CBMAB-S4981-CQ)

Name: Mouse Anti-SLC38A4 Recombinant Antibody (CBXS-2219)
SKU: CBMAB-S4981-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-2219

Application

WB, IP, IF, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Solute Carrier Family 38 Member 4

Introduction

SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001 [PubMed 11342143]).

Entrez Gene ID

55089

UniProt ID

Q969I6

Alternative Names

Solute Carrier Family 38 Member 4; Na(+)-Coupled Neutral Amino Acid Transporter 4; System A Amino Acid Transporter 3; System N Amino Acid Transporter 3; Amino Acid Transporter A3; SNAT4; NAT3;

Function

Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane (PubMed:11342143, PubMed:19015196, PubMed:33928121).
The transport is electrogenic, pH dependent and partially tolerates substitution of Na+ by Li+ (PubMed:11414754).
Preferentially transports smaller amino acids, such as glycine, L-alanine, L-serine, L-asparagine and L-threonine, followed by L-cysteine, L-histidine, L-proline and L-glutamine and L-methionine (PubMed:11414754, PubMed:33928121).

Biological Process

Biological Process amino acid transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process amino acid transportTAS:Reactome
Biological Process sodium ion transportIEA:UniProtKB-KW

Cellular Location

Cell membrane
Cell projection, microvillus membrane
Microvillus membrane localization in placenta.

PTM

The disulfide bond plays an important role in substrate transport, but has no effect on trafficking to the cell surface.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-SLC38A4 Recombinant Antibody (CBXS-2023) (CAT#: CBMAB-S4790-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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