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Rabbit Anti-SLC47A1 Recombinant Antibody (CBFYM-3128) (CBMAB-M3325-FY)

This product is rabbit antibody that recognizes SLC47A1. The antibody CBFYM-3128 can be used for immunoassay techniques such as: WB, IP.
See all SLC47A1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBFYM-3128
Application
WB, IP

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Solute Carrier Family 47 Member 1
Introduction
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.
Entrez Gene ID
55244
UniProt ID
Q96FL8
Alternative Names
Solute Carrier Family 47 Member 1; Solute Carrier Family 47 (Multidrug And Toxin Extrusion), Member 1; Multidrug And Toxin Extrusion 1; HMATE-1; MATE-1; MATE1; Multidrug And Toxin Extrusion Protein 1
Function
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
Biological Process
Biological Process amino acid import across plasma membraneManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process L-alpha-amino acid transmembrane transportManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process L-arginine import across plasma membraneManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process organic cation transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transmembrane transportTAS:Reactome
Biological Process xenobiotic detoxification by transmembrane export across the plasma membraneIEA:InterPro
Biological Process xenobiotic transportManual Assertion Based On ExperimentIMP:ARUK-UCL
Cellular Location
Cell membrane
Predominantly localized at the plasma membrane but also found in intracellular organelles.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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