Rabbit Anti-SLC47A1 Recombinant Antibody (CBFYM-3128) (CBMAB-M3325-FY)

Name: Rabbit Anti-SLC47A1 Recombinant Antibody (CBFYM-3128)
SKU: CBMAB-M3325-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBFYM-3128

Application

WB, IP

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Solute Carrier Family 47 Member 1

Introduction

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.

Entrez Gene ID

55244

UniProt ID

Q96FL8

Alternative Names

Solute Carrier Family 47 Member 1; Solute Carrier Family 47 (Multidrug And Toxin Extrusion), Member 1; Multidrug And Toxin Extrusion 1; HMATE-1; MATE-1; MATE1; Multidrug And Toxin Extrusion Protein 1

Function

Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Biological Process

Biological Process amino acid import across plasma membraneManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process L-alpha-amino acid transmembrane transportManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process L-arginine import across plasma membraneManual Assertion Based On ExperimentIMP:ARUK-UCL
Biological Process organic cation transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transmembrane transportTAS:Reactome
Biological Process xenobiotic detoxification by transmembrane export across the plasma membraneIEA:InterPro
Biological Process xenobiotic transportManual Assertion Based On ExperimentIMP:ARUK-UCL

Cellular Location

Cell membrane
Predominantly localized at the plasma membrane but also found in intracellular organelles.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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